There are a few variants, but yes, most of them are just mindless repetition x1000.
The variants that come to mind are>Battle Cats standard events
Which essentially you clear once, then clear twice more on higher stat modifiers, then the final difficulty restricts the units you can use to either normal/special (i.e. no gacha units) or Rare/Special (i.e. only the game's equivalent of 1* units + the other non-gacha ones). Granted this is because Battle Cats is rather old.>Rank mode competitive ones, which typically necessitate only one or two clears depending on the game
E.g. Crash Fever had Rank Quests and most of the time I'd get all the score shit first go around then do a tryhard run to up my global rank.>Singleplayer unique events
E.g. Arknights Contingency Contract series, which pits you against a main stage and a daily stage, both of which you can do as many times as you want in a day but they have a set amount of rewards. Each player picks "risks" that raise the difficulty (e.g. deployment block, removes a team slot, enemies behave differently, stage layout changes, etc.) and higher risk total clears missions up to a point. Not a grinding event, and overall one of the better gacha event handlings that I've seen.>"Roguelike" events
Fire Emblem Heroes and the aforementioned Arknights have both had their own versions of this. Fire Emblem specifically limits the amount of clears to 3 per day so it's not a repetition event, but Arknights does make you repeat it for the prizes. Depends on the game.
Overall, there aren't too many instances of events that aren't "set on auto 5 billion times" but they do exist.