They'd definitely be getting PPP loans. Prolly get Artie one too since his restaurant would be cratering.
Melfie would try to set up telehealth therapy by Zoom but Tony would lose his mind, so she'd meet with him 1on1 and only him.
She'd demand he wear a mask, James Gandolfini's expressive eyes influence the writing team into having Melfi fall for Tony instead of being the moral center of the series.
99% of the crew disagrees with the mask mandates, vaccine mandates, but >>156409381
Fauci is a pisano so he's got some clout. Carm's father dies to COVID, she swings from anti-masker to pro-masker (AJ is avidly anti-mask but pro-vaccine; Meadow double masks, gets vaxxed early) and pressures Tony into agreeing; so now he has both women in his life pressuring him into the same corner. NY sees NJ as weak cause Tony's crew masks up.
Tony finds out one of the strippers at the BING is COVID positive but asymptomatic and sends her into a NY crew party to infect them. COVID incapacitates a boss, multiple underbosses, and good NY earners.
NJ gets wind of monoclonal antibodies and starts looking to hijack trucks of doses.
Some hijinks ensue during the part where Tony is being pressured to mask up, some underlings are caught gouging N95 mask prices and Tony blows his top at them, yelling incorrectly remembered facts Fauci mentioned during a TV interview 2 episodes prior.